CLinically Back Vegan Protein
Explore research supporting YESTEIN® across protein digestibility, muscle recovery, whey-equivalent nutrition, gut health, and calcium absorption & bone health.
PDCAAS 1.0 supports high protein quality and digestibility.
Complete protein with ≥20% BCAA supports muscle recovery.
Clinical research supports muscle outcomes comparable to whey.
Research suggests benefits beyond protein, including digestive support.
Studies suggest support for calcium absorption and bone health.
PDCAAS
High Digestibility
Yeast Protein has a PDCAAS of 1.0 based on five lots of amino acid profile analysis and an in vitro protein digestibility score of 92.5% ± 2.5%.⁴
The PDCAAS of Yeast Protein is at the same level as WPC (whey protein concentrate) and higher than SPI (soy protein isolate) for adults.⁴
Yeast Protein increases the digestibility and absorption rate of proteins when used as a complementary protein in blends.²
Lean Muscle & Recovery
Human kinetic studies verify rapid synthesis rates ideal for modern exercise nutrition.
Exceptional Amino Acid Profile
A naturally complete source boasting a PDCAAS of 1.00, a perfect biological score.
Gut Health & Tolerability
No gas, bloating or discomfort associated with traditional dairy whey or heavy bean isolates.
BCAA & MUSCLE HEALTH
Supports Muscle Recovery
Yeast Protein is high in branched-chain amino acids, which are converted into glucose when broken down—helping prevent muscle loss and promote recovery after exercise.¹
Experimental results showed that Yeast Protein contains ≥20.0% BCAA, higher than PPI and comparable to WPC.
Yeast Protein is an excellent protein for sports nutrition and an aging population, supporting muscular recovery and helping reduce muscular fatigue and loss.
Yeast Protein increases lean muscle mass, strength, and endurance when consumed twice daily at 20 g per dose for eight weeks alongside exercise in an aging population aged 40 and older.⁵
Yeast Protein improves muscle morphology, strength, and size, and helps reverse muscle loss when combined with resistance training at a recommended intake of 1 g/kg body weight daily for three months.³
NUTRITION
Whey Equivalency
Participants: 116 healthy adult males aged 40 and older were recruited, with 79 completing the study.
Intervention: Participants were randomly assigned to consume 20g of Yeast Protein, whey protein, or a maltodextrin placebo twice daily for eight weeks.
Exercise regimen: Participants engaged in resistance training three times each week.
Measurements: Body composition via DEXA scans, muscle strength, and endurance were assessed at baseline, week four, and week eight.
Results
Yeast Protein is an effective and sustainable alternative to whey protein for improving lean mass, strength, and endurance in adults, particularly those with low protein intake.⁵
The Yeast Protein and whey protein groups increased lean trunk mass and total lean mass from baseline.⁵
Digestion
Gut Health
Study model: A preclinical ex vivo SIFR® study compared yeast, whey, and soy proteins following simulated digestion.
Donor samples: Gut microbiota were collected from six healthy men aged 50–65.
Intervention: Proteins were tested at an amount modeled to represent 40 g per day, alongside a no-substrate control.
Measurements: Researchers assessed microbial changes, metabolites, gas production, inflammatory markers, and gut-barrier integrity over 24 hours.
Results
Yeast protein produced the strongest gut-barrier response among the three protein sources, indicated by increased TEER in the ex vivo host–microbiome interaction model.⁶
Yeast and soy proteins produced the largest increases in the study’s combined community-modulation score, suggesting broader stimulation of donor microbiota. Yeast protein also promoted butyrate-associated microbial activity.⁶
Yeast protein generated less gas relative to total SCFA production than whey or soy protein, suggesting a potentially more favorable fermentation profile in this ex vivo model.⁶
Bone Health
Calcium absorption, part of the nutrient story.
Yeast Protein may support calcium absorption and retention, helping improve how calcium is utilized within the body.⁷
Research found that combining Yeast Protein with calcium supported bone calcium content, bone formation markers, and biomechanical strength.
Yeast-derived proteins may help bind calcium and support its sustained release, creating potential for use in calcium-fortified and healthy-aging formulations.⁷
These findings suggest YESTEIN® is a promising protein ingredient for future bone-health and healthy-aging formulations.⁷
Resources
See references
